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Seo jang hoon wife sexual dysfunction

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All data generated or analysed during this study are included in this published article. Hypercholesterolaemia HC is a major risk factor for ischemic heart disease and is also known to be a risk factor for erectile dysfunction ED.

ED caused by HC is thought to be related to HC-induced oxidative stress damage in the vascular endothelium and erectile tissue. KH is an herbal formula with a strong antioxidant effect. Normal control group rats were fed normal chow diet. Subsequently, intracavernous pressure ICP and mean arterial pressure MAP were measured, and lipid profiles, expression of endothelial eNOS and neuronal nNOS nitric oxide synthase, oxidative stress 8-hydroxydeoxyguanosineand ratio of smooth muscle cells Seo jang hoon wife sexual dysfunction collagen fibres were evaluated in the serum and corpora tissue.

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The current study shows that the antioxidant and hypolipidemic effects of KH are effective in ameliorating ED by restoring endothelial dysfunction and suggests that KH may be a potential therapeutic agent for ED by correcting the fundamental cause of ED. Penile erection is a complex physiological process that occurs through a cascade of neurogenic, vascular, and humoral events.

To Seo jang hoon wife sexual dysfunction a penile erection for satisfactory sexual intercourse, important preconditions are necessary, including proper cavernosal innervation, maintenance of endothelial function, and well-functioning erectile tissue.

Erectile dysfunction EDdefined as the consistent inability to attain or maintain a penile erection of sufficient quality to permit satisfactory sexual intercourse [ 1 ], is a highly prevalent global health problem with considerable impact on the quality of life of middle-aged men [ 2 ].

ED can be induced by various causes, including arterial, neurogenic, hormonal, cavernosal, iatrogenic, and psychogenic causes. However, the most common cause is likely related to vascular abnormalities caused by endothelial dysfunction and erectile tissue dysfunction [ 34 ].

Hypercholesterolaemia HC is a metabolic disorder characterized by elevated levels of total cholesterol TC in the blood. HC may develop as a consequence of an unbalanced diet, obesity, inherited genetic disease familial hypercholesterolaemiaor another disease e. It is well known that HC is a major risk factor for the development of atherosclerosis and subsequent ischemic heart disease [ 6 ].

Elevated serum cholesterol and reduced high-density lipoprotein cholesterol HDL-C levels are also associated with an increased risk of ED [ 7 ]. The relationship between ED and HC has been demonstrated by several studies [ 89 ].

Although the mechanism underlying the increased ED risk by HC has not Seo jang hoon wife sexual dysfunction clearly elucidated, many studies reported an association between HC-induced oxidative stress damage in vascular endothelium and erectile tissue and ED [ 10 — 12 ].

We evaluated the effects of...

Seo jang hoon wife sexual dysfunction KH is an herbal formula composed of Cornus officinalis Sieb. Several studies have reported that each herb or various combinations of these herbs have a number of beneficial properties, including antioxidant [ 13 — 18 ], anti-inflammatory [ 1519 ], anti-apoptotic [ 172021 ], anti-fibrotic [ 152223 ], and hypolipidemic effects [ 2425 ] in multiple diseases.

These herbs have been widely used in Korea as medicines for many years. Ojayounjonghwon, an herbal formula described in Dong Ui Bo Gam a representative of Korean traditional medicine booksincludes four of the above herbs, with the exception of Cornus officinalis Sieb.

KH is a new herbal formula that is a modified form of Ojayounjonghwon. In addition, Sohn et al. We hypothesized the improvement of erectile function by KH treatment was attributable to its antioxidant effects. The aim of the present study was to assess the effects of HC on the quality of erections and to evaluate the effects of KH treatment in a rat model of ED induced by HC.

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